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Chemical Investigation And Antihepatotoxic Activity Of The Fruits Of Lagenaria Siceraria

Author(s): Annie Shirwaikar, K. K Sreenivasan

The antihepatotoxic activity of different fractions of the ethanolic extract of Lagenaria siceraria fruit, administered orally to different groups of rats was evaluated using the CCl4- Induced hepatotoxicity test. All fractions tested, in a dose of 250 mg/kg showed significant activity, with the petroleum ether fraction exhibiting comparatively higher activity. Two steroids were isolated from the petroleum ether fraction and they were identified as fucosterol and campesterol.


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