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Abstract

Clinical Efficacy of Esculin and Digitalis Glycosides Eye Drops in Visual Acuity Recovery after Femtosecond Laser Surgery

Author(s): H. Li, L. Shi, Xueqing Wang and L. Xia*
Department of Ophthalmology, Shengjing Hospital, China Medical University, Shenyang, Liaoning Province 110004, China

Correspondence Address:
L. Xia, Department of Ophthalmology, Shengjing Hospital, China Medical University, Shenyang, Liaoning Province 110004, China, E-mail: Xialksj@163.com


This study seeks to examine the clinical efficacy of esculin and Digitalis glycosides eye drops in facilitating visual acuity recovery after femtosecond laser surgery. Between May 2021 and May 2022, a total of 120 patients (240 eyes) who underwent femtosecond laser corneal refractive surgery at the department of ophthalmology were randomly assigned to either the observation group or the control group. Each group consisted of 60 cases (120 eyes). Femtosecond laser in situ keratomileusis treatment was administered to both groups, with the control group additionally receiving conventional treatment post-surgery comprising of steroids, antibiotics, and artificial tears. Alongside the standard treatment, the observation group was administered esculin and Digitalis glycosides eye drops. The uncorrected visual acuity and refractive error of the patients were compared before and after surgery, and their visual satisfaction was evaluated. No notable disparity in uncorrected visual acuity was found between the two groups before the operation and at the 1 w postoperative assessment. Nonetheless, at the 1 mo follow-up, the uncorrected visual acuity of the observation group showed a significant improvement compared to the control group (p<0.05). The refractive error between the two groups did not show any significant difference prior to surgery (p>0.05). Nonetheless, after 1 w and 1 mo of surgery, the observation group displayed significantly lower refractive error compared to the control group. The observation group exhibited a significantly higher degree of visual satisfaction in comparison to the control group, demonstrating a statistically significant difference (p<0.05). Esculin and Digitalis glycosides eye drops, as an auxiliary treatment for visual acuity recovery after femtosecond laser surgery, can significantly improve uncorrected visual acuity and refractive error and increase visual satisfaction.

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