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Abstract

Clinical Efficacy of Nimodipine and Edaravone Combination in the Treatment of Acute Cerebral Hemorrhage

Author(s): SUZHEN WANG*, XIAOQIN AN1, YUEHUA WANG, JIXIN ZHANG, LIGUO QI2
Department of Neurosurgery,1Department of Neurology, Shandong Jiyang Public Hospital, Jinan 251400, China, 3Department of Neurosurgery, Taian Central Hospital, Taian 271000, China

Correspondence Address:
Department of Neurosurgery,Shandong Jiyang Public Hospital, Jinan 251400, China, E-mail: [email protected]

To observe and analyze the clinical efficacy of nimodipine and edaravone combination in the treatment of acute cerebral hemorrhage, a total of 180 patients definitely diagnosed as acute cerebral hemorrhage and treated in Shandong Jiyang Public hospital were enrolled. The patients were divided into the control group and the research group with 90 patients in each group. Of those, patients of the control group were treated with edaravone, while a combination of nimodipine and edaravone was administered to patients in the research group. Therapeutic efficacy, neurologic impairment score, life quality score, hematoma volume and edema volume were compared between both the groups. Results obtained showed that the total therapeutic efficacy of the research group was better than that of the control group (P<0.05). Measurement of patients’ hematoma volume and edema volume before and after treatment indicated that the research group after drug administration demonstrated significant improvement over the control group (P<0.05). Moreover, there was a greater decrease in the neurologic impairment score of the research group than that of the control group (P<0.05). Combination of nimodipine and edaravone in the treatment of acute cerebral hemorrhage achieved better outcomes indicating greater therapeutic efficacy.

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