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Abstract

Clinical Observation of Sodium Hyaluronate Combined with Ropivacaine after Anterior Cruciate Ligament Reconstruction under Knee Arthroscopy

Author(s): Peng Chen*, Defu Yu, Biao Zhang and Tao Chen
Department of Orthopedics, Anhui No. 2 Provincial People's Hospital, Hefei, Anhui province 230000, China

Correspondence Address:
Peng Chen, Department of Orthopedics, Anhui No. 2 Provincial People's Hospital, Hefei, Anhui province 230000, China, E-mail: woshicpjiayou@163.com


The primary objective of this investigation was to assess the clinical effectiveness of utilizing sodium hyaluronate in conjunction with ropivacaine for postoperative management after arthroscopic anterior cruciate ligament reconstruction. From March 2019 to March 2021, a cohort of 150 patients with anterior cruciate ligament rupture who underwent anterior cruciate ligament reconstruction surgery were recruited for this study. The patients were randomly allocated into either the observation group or the control group, with each group comprising 75 cases. The control group received intra-articular injection of ropivacaine after surgery, while the observation group received intra-articular injection of sodium hyaluronate combined with ropivacaine after surgery. A comparative analysis was performed to compare the Lysholm knee score, visual analogue scale score, and the levels of tumor necrosis factor-alpha and interleukin-1 beta in joint fluid between the observation group and the control group. The observation group demonstrated a higher overall effective rate (93.3 %) compared to the control group (86.7 %), with statistical significance (p<0.05). No significant differences were found in preoperative Lysholm score, visual analogue scale score and joint fluid parameters between groups. The observation group showed significant improvements compared to the control group, as shown by a higher postoperative Lysholm score, lower visual analogue scale score (p<0.05) and reduced levels of inflammatory markers in joint fluid (p<0.05). Sodium hyaluronate combined with ropivacaine after anterior cruciate ligament reconstruction surgery under arthroscopy can promote knee joint function recovery, alleviate postoperative pain, suppress oxidative and inflammatory stress in the joint, and contribute to impr oving patient prognosis.

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