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Abstract

Clinical Study on the Efficacy of Pantoprazole Combined with Mosapride on Gastroesophageal Reflux Chest Pain

Author(s): Chang Hui, G. Yingqiang, Yang Zhicai, N. Xiaokang and Yue Liming*
Department of Cardiovascular Medicine, Affiliated Hospital of Shaanxi University of Chinese Medicine, Shaanxi, P.R. China

Correspondence Address:
Department of Cardiovascular Medicine, Affiliated Hospital of Shaanxi University of Chinese Medicine, Shaanxi, P.R. China, E-mail: [email protected]

To analyze the efficacy of pantoprazole combined with mosapride on gastroesophageal reflux chest pain. A total of 74 patients with gastroesophageal reflux chest pain treated in the Hospital of Shaanxi from June 2016 to June 2017 were enrolled in the study and divided into 2 groups, the combined group and the reference group (n=37) according to the order of admission. The combined group received treatment of pantoprazole and mosapride while the reference group was treated with pantoprazole. Curative effect, recurrence rate and gastroesophageal reflux disease symptom frequency scale were compared between the two groups. The total effective rate of the reference group was 83.78 %, significantly lower than that of the combined group (97.3 %, p>0.05). Besides, there were 2 cases of recurrence in the combined group, while there were 7 cases in the reference group and this difference is statistically significant (p<0.05). Meanwhile, after treatment the gastroesophageal reflux disease symptom scores of patients in the combined group were significantly better than those in the reference group. The combined treatment of pantoprazole and mosapride has significant curative effect on gastroesophageal reflux chest pain with relatively high effective rate, thus worthy of recommendation in clinical trials.

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