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CNS Depressant Activity Of Ethanol Extract Of Luffa Acutangula Var. Amara C. B. Clarke Fruits In Mice

Author(s): A. V Misar, A. S Upadhye, A. M Mujumdar

The fruits of Luffa acutangula Var. amara C. B. Clarke were collected in winter season from Western ghat area. These fruits were dried, powdered, defatted and extracted with ethanol. HPTLC pattern of ethanol extract was recorded after removal of solvent and was studied for effect on behavioral changes, exploratory activity, barbiturate sleeping time, using appropriate standards in mice. The extract exhibited dose-dependent CNS depressant activity.


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