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Abstract

Colorimetric determination of ibuprofen in tablets.

Author(s): YK Agarwal, S Patel
Pharmacy Dept., Faculty of Technology and Engineering, M.S. University of Baroda, Kalabhavan, Baroda 390 001,

Correspondence Address:
Y K Agarwal Pharmacy Dept., Faculty of Technology and Engineering, M.S. University of Baroda, Kalabhavan, Baroda 390 001

A simple extraction and colorimetric method for the determination of ibuprofen in its dosage form based on the conversion of carboxylic acid into an acid chloride and its coupling with hydroxylamine to get hydroxamic acid which forms a violet coloured complex with vandium in acidic medium is described.

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