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Colourimetric Estimation Of Cisapride Using Iodine-Catechol Charge Tansfer Complex Formation

Author(s): K. R Krishnakumar, R Raju

Cisapride is a substituted piperidinyl benzamide chemicaly related to metoclopramide. Its full chemical name is (±) cis-4-amino - 5 - chloro -N [1-[3-(4- flurophenoxy) propyl] ] -3-methoxy-4-piperidinyl]-2- methoxybenzamide.[1]. The reported methods of analysis are the non-aqueous potentiometric method using Ag/AgC1 electrode[2] and the HPLC UV detection method, for the estimation from body fluids[3]. In the present communication the development of a colourimetric method based on charge transfer (CT) complex formation of cisapride with iodine and catechol is reported.


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