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Abstract

Combined Efficacy of Pregabalin and Suspension System in Lumbar Disc Herniation and its Impact on JOA and ODI Score

Author(s): K J. Xue, L. Zhang, Junliang Jiang*, H. Yang, Peijia Jing, Zhuo Wang, S. Xiao, Yue Hou and Jingyu Zhao
Department of Rehabilitation Medicine, West China Hospital of Sichuan University, Chengdu, Sichuan 610041, 1School of Physical Education and Health, Chengdu University of Traditional Chinese Medicine, Chengdu, Sichuan 610075, 2Department of Pharmacy, West China Hospital of Sichuan University, Chengdu, Sichuan 610041, China

Correspondence Address:
Junliang Jiang, Department of Rehabilitation Medicine, West China Hospital of Sichuan University, Chengdu, Sichuan 610041, China, E-mail: jjlhxkf@scu.edu.com


People diagnosed with lumbar disc herniation-associated low back pain were recruited from our hospital between January 2020 and October 2022. They were randomized into two groups; control group (n=150) underwent pregabalin treatment, while the experimental group (n=150) received a combination of pregabalin and suspension exercise suspension system treatment. The study compared the therapeutic effect, lumbar function, muscle strength and pain between the two groups before and 4 w after treatment. The total effective rate of treatment in the test group, which received pregabalin combined with suspension exercise suspension system, was 94.00 %, significantly higher than that of the control group (87.33 %) (p<0.05). After 4 w of treatment, both groups showed an increase in the functional independence scale score and a decrease in the oswestry index score. Moreover, in the experimental group, the functional independence scale score was significantly higher compared to that of the control group, while the oswestry index score was significantly lower. The extensor and flexor muscle strength of both groups also improved after 4 w of treatment, but the test group had significantly higher strength compared to the control group (p<0.05). The Japanese orthopaedic association score increased and the visual analog scale score decreased after 4 w of treatment in both groups. The experimental group showed significantly higher Japanese orthopaedic association score than the control group and a lower visual analog scale score than the control group. In the management of low back pain caused by lumbar disc herniation, pregabalin combined with suspension exercise suspension system exhibits a remarkable therapeutic effect. It aids in reducing the intensity of low back pain while enhancing lumbar muscle strength, ultimately fostering a functional recovery of the lumbar region.

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Citations : 66710

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