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Comparative evaluation of rice bran wax as an ointment base with standard base

Author(s): Vidya Sabale1, PM Sabale2, CL Lakhotiya3
1 Parul Arogya Seva Mandal's Baroda College of Pharmacy, Limda, Vadodara-391 760, India 2 Pharmacy Department, Faculty of Technology and Engineering, The M. S. University of Baroda, Vadodara-390 001, India 3 Department of Pharmaceutical Sciences, R. T. M. Nagpur University, Nagpur-440 010, India

Correspondence Address:
Vidya Sabale Parul Arogya Seva Mandal's Baroda College of Pharmacy, Limda, Vadodara-391 760 India [email protected]

Waxes have been used in many cosmetic preparations and pharmaceuticals as formulation aids. Rice bran wax is a byproduct of rice bran oil industry. Present investigation has been aimed to explore the possible utility of rice bran wax as ointment base compared to standard base. The rice bran wax obtained, purified and its physicochemical characteristics were determined. Ointment base acts as a carrier for medicaments. The ointment base composition determines not only the extent of penetration but also controls the transfer of medicaments from the base to the body tissues. Rice bran wax base was compared with standard base for appearance, spreadability, water number, wash ability and diffusibility. The results show that rice bran wax acts as an ointment base as far as its pharmaceutical properties are concerned and it could effectively replace comparatively costlier available ointment bases.

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Citations : 53647

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