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Comparative Molecular Field Analysis (CoMFA) : A Modern Approach Towards Drug Design

Author(s): L. G Rathi, Sushil K Kashaw, R. K Agrawal, P Mishra

The Comparative Molecular Field Analysis (CoMFA) approach permits analysis of a large number of quantitative descriptors and uses chemometric methods such as partial least squares (PLS) to correlate changes in biological activity with changes in chemical structure. It is one of the most robust modern tools for quantitative structure activity relationship studies. This review gives the introductory overview and general methodology used to carry out CoMFA.


Google scholar citation report
Citations : 53647

Indian Journal of Pharmaceutical Sciences received 53647 citations as per google scholar report