All submissions of the EM system will be redirected to Online Manuscript Submission System. Authors are requested to submit articles directly to Online Manuscript Submission System of respective journal.

Abstract

Comparison of the Clinical Efficacy of Proximal Femoral Nail Antirotation and Femoral Head Replacement on Intertrochanteric Fracture and the Influence of Tartrate Resistant Acid Phosphatase 5b and Bone Alkaline Phosphatase

Author(s): G. H. Ma and Y. L. Wu*
Department of Extra osseous, Qixia City People’s Hospital, Qixia, Shandong 265300, 1Department of orthopaedics, Lai Zhou City People’s Hospital, No. 1718, Wuli Street, Laizhou, Shandong 261400, China

Correspondence Address:
Y. L. Wu, Department of orthopaedics, Lai Zhou City People’s Hospital, No. 1718, Wuli Street, Laizhou, Shandong 261400, China, E-mail: [email protected]


To explore the clinical efficacy of proximal femoral nail antirotation and femoral head replacement in the treatment of intertrochanteric fracture of femur and to explore the effect of tartrate resistant acid phosphatase 5b and bone alkaline phosphatase. 100 patients with intertrochanteric fracture of femur from January 2017 to January 2020 in our hospital were selected and randomly divided into proximal femoral nail antirotation group (n=50) and femoral head replacement group (n=50). The operation time, intraoperative blood loss, postoperative weight bearing time, length of hospital stay, Harris score, tartrate resistant acid phosphatase 5b, bone alkaline phosphatase level and complications were compared between the two groups. Compared with femoral head replacement group, the operation time, intraoperative blood loss, postoperative weight bearing time and hospitalization time of proximal femoral nail antirotation group were significantly increased (p<0.05). Compared with before operation, Harris score of two groups were significantly increased after operation and the increase of femoral head replacement group was significantly greater than that of proximal femoral nail antirotation group (p<0.05). Compared with before operation, tartrate resistant acid phosphatase 5b was significantly lower, bone alkaline phosphatase was significantly higher and femoral head replacement was significantly higher in the two groups after operation (p<0.05). Compared with femoral head replacement group (16.00 %), the incidence of complications in proximal femoral nail antirotation group (6.00 %) was significantly lower (p<0.05). Compared with proximal femoral nail antirotation, femoral head replacement in the treatment of intertrochanteric fracture of femur has shorter postoperative weight bearing time and hospitalization time, which is more conducive to the recovery of hip joint function and improvement of bone metabolism indexes. However, femoral head replacement has longer operation time, more bleeding and higher risk of postoperative complications, which has a good reference value for clinical treatment of intertrochanteric fracture of femur.

Full-Text | PDF

 
 
Google scholar citation report
Citations : 53647

Indian Journal of Pharmaceutical Sciences received 53647 citations as per google scholar report