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Abstract

Correlation Analysis of Postoperative Recurrence and Metastasis of Renal Cancer with Type 2 Diabetes Mellitus

Author(s): Yang Liu, Lingling Meng*, Jianwei Li, Gui Song Qi and Miaomiao Song
Department of Urology, 1Department of Endocrinology, Cangzhou Central Hospital of Hebei Province, Cangzhou, Hebei 061000, China

Correspondence Address:
Lingling Meng, Department of Endocrinology, Cangzhou Central Hospital of Hebei Province, Cangzhou, Hebei 061000, China, E-mail: menglingling2015@163.com


To analyze the correlation between alcohol consumption, smoking, duration of diabetes and postoperative recurrence and metastasis in renal cancer patients who underwent nephrectomy in our hospital from April 2018 to January 2020 were selected as the research subjects. According to the recurrence and metastasis of the patients within 2 y after the operation, the patients were divided into drinking, smoking and diabetes duration in recurrence and metastasis group and non-relapse and metastasis group was analyzed and Pearson correlation was used to analyze drinking, smoking and diabetes duration and renal cancer patients with type 2 diabetes after surgery correlation of recurrence and metastasis. The proportion of patients with drinking, smoking and diabetes duration ≥5 y in the recurrence and metastasis group. The results of the correlation analysis of postoperative recurrence and metastasis in patients with type 2 diabetes showed that drinking, smoking and the duration of diabetes were positively correlated with the occurrence of postoperative recurrence and metastasis in patients with renal cancer combined with type 2 diabetes (r=0.631, p=0.000; r=0.640, p=0.000; r=0.593 and p=0.000); logistic regression analysis showed that drinking, smoking and duration of diabetes were independent risk factors for postoperative recurrence and metastasis in patients with renal cancer complicated with type 2 diabetes (p<0.05). The drinking, smoking and duration of diabetes in renal cancer patients with type 2 diabetes are closely related to their recurrence and metastasis within 2 y after surgery. However, its specific mechanism of action still needs further research and verification.

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