Abstract

Author(s): K. M Bhat, V Kumar, K. I Molvi, N. S Parmar

A new spectrophotometric method for the assay of atropine sulphate has been developed. This utilized the well known reaction of tropic acid, Vitalimonium reaction. The sample when digested with nitric acid and treated with 3% methanolic potassium hydroxide develops a blue chromophore. The absorbance of the resulting solution was measured exactly after one minute at 570 nm. This method has a linearity range of 2-20 µg/ml and compares well with official procedure.

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