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Effect of hydrophobic binding agents on dissolution of sulphadimidine tablets

Author(s): YV Pathak, AK Dorle
College of Pharmacy, Manipal 576 119,

Correspondence Address:
Y V Pathak College of Pharmacy, Manipal 576 119

Sulfadimidine (SD) tablets were prepared using various rosin derivatives as a binding agent. These were compared with marketed Sulfadimidine Tablets I.P. Two formulations with pentaerythritol rosin ester and rosin maleic acid adduct esterified with glycerol as binding agents have shown statistically significant decrease in the dissolution time of SD tablets as compared to the controls.