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Abstract

Efficacy of Amiodarone on the Heart Failure Patients with Arrhythmia

Author(s): Mingyi Lv and X. F. Long*
Department of Internal Medicine Intensive Care Unit, Affiliated Zhongshan Hospital of Dalian Universtity, Dalian, Liaoning 116001,China

Correspondence Address:
X. F. Long, Department of Internal Medicine Intensive Care Unit, Affiliated Zhongshan Hospital of Dalian Universtity, Dalian, Liaoning 116001,China, E-mail: longxiaofeng88@sina.com


To investigate the efficacy of amiodarone on the heart failure patients with arrhythmia is the objective of the study. Between April 2018 and April 2020, 86 heart failure patients with arrhythmia who were admitted to the hospital for treatment were enrolled into the study and numbered, and according to the sequence of admission, they were randomized into the control group and observation group, with 43 patients in each group. Patients in two groups received the regular medication, while those in the observation group additionally took amiodarone. We measured the hemodynamic parameters of patients in two groups before and after treatment, including the mean arterial pressure, cardiac output, cardiac index, ejection fraction, fractional shortening and maximal flow velocity in early diastolic stage/maximal flow velocity in advanced diastolic stage, evaluated the efficacy and recorded the incidence rate of adverse reactions. Following the treatment, the effectiveness rate of patients in the observation group was significantly higher than that in the control group (c2=3.927, p<0.05), while the difference in the incidence rates of adverse reactions showed no statistical significance (p>0.05). Amiodarone in treatment of heart failure patients with arrhythmia can improve the heart function and efficacy, and thus it is safe and efficient in clinical practice.

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Citations : 66710

Indian Journal of Pharmaceutical Sciences received 66710 citations as per google scholar report