Abstract
Efficacy of Bailing Capsule (Traditional Chinese Medicine) in the Treatment of Nephrotic Syndrome: A Meta-analysis
Department of Purchasing, Liaocheng Second People's Hospital, Shandong, PR China 650032, 1Department of Pharmacy, Liaocheng Second People's Hospital, Shandong, PR China 650032, 1Department of Pharmacy, 2Department of Imaging, Jinan Central Hospital, Shandong, China 650500, 3Department of Gastroenterology, Medical Institute of Guizhou Medical University, Guizhou, PR China 550000
Correspondence Address:
Department of Gastroenterology, Medical Institute of Guizhou Medical University, Guizhou, PR China, E-mail: tianshi8552853@163.com
Meta-analysis of the existing literature on the treatment of nephrotic syndrome with Bailing capsule in adult patients was carried out to provide evidences for clinical practice. Relevant articles describing the effect were included. A total of 5 documents were selected. The meta-analysis showed that Bailing capsule reduced 24 h urine protein in patients with nephrotic syndrome (standardized mean difference=2.35 (3.72, 0.97), p<0.01), increased the level of serum albumin (standardized mean difference=0.94 (0.37, 1.52), p=0.01), but had no improvement on serum creatinine (standardized mean difference=0.50 (1.25, 0.26), p=0.20) as well as blood urea nitrogen (standardized mean difference=0.10 (0.36,0.17), p=0.48). The adjuvant treatment of nephrotic syndrome with Bailing capsule could reduce proteinuria, enhance plasma albumin and decrease blood lipids in patients. However, these conclusions need to be confirmed by further clinical trials.
