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Abstract

Efficacy of Human Interferon Alpha-2b Spray Combined with Chiqiao Qingre Granule in the Treatment of Herpangina in Children

Author(s): Li Luo, Lingjun Xu, K. Chi and Anming Xie*
Department of Emergency Medicine, Jiangxi Provincial Children???s Hospital, Nanchang, Jiangxi 330006, 1Department of Radiology, The 908th Hospital of Chinese People???s Liberation Army Joint Logistic Support Force, Nanchang, Jiangxi 330002, China

Correspondence Address:
Anming Xie, Department of Radiology, The 908th Hospital of Chinese People???s Liberation Army Joint Logistic Support Force, Nanchang, Jiangxi 330002, China, E-mail: Xieam76@163.com


The objective of this study was to evaluate the efficacy and safety of treating herpangina in children using interferon alpha-2b spray combined with Chiqiao Qingre granule. Over a period from January 2021 to December 2022, 240 children with herpangina who were treated at our hospital were randomly divided into four groups; group A received routine treatment, group B was treated with interferon alpha-2b, group C was treated with Chiqiao Qingre granule, and group D was treated with a combination of interferon alpha-2b and Chiqiao Qingre granule. The symptom regression time, serum inflammatory levels, and adverse reactions were observed and compared for 5 d. Interferon alpha-2b, Chiqiao Qingre granule and their combination treatment group all achieved better curative effect, and the combination of interferon alpha-2b and Chiqiao Qingre granule could bring better results, and the difference was not significant in the safety between combined treatment and routine treatment, interferon alpha-2b and Chiqiao Qingre granule alone. The combination of interferon alpha-2b and Chiqiao Qingre granule is an effective and safe therapy for children.

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