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Efficacy of Micronutrient Supplementation During Antenatal Period: An Open Label Randomized Control Trial

Author(s): S. Thomas, Gomathi Marimuthu, Pooja Sudarsan, Arun Kanniyappan Parthasarathi And Deepalakshmi Mani*
Correspondence Address:
Department of Pharmacy Practice, School of Pharmacy, College of Pharmacy and Nursing, University of Nizwa, Oman, 1Department of Pharmacy Practice, JSS College of Pharmacy, JSS Academy of Higher Education and Research, Ooty 643001, Tamil Nadu, India

An open label randomized control trial was conducted to evaluate the efficacy of micronutrients among pregnant women and assessing the antenatal and fetal complications associated with the same. The participants were randomized into intervention and control groups. The intervention group was administered with micronutrient supplementation. Demographic characteristics were captured following which analysis was done. The distribution of the demographic characteristics was assessed using independent t test and Chi square test. Multivariate analysis was performed to find the efficacy of micronutrients in terms of gestational week, body mass index, blood pressure, maternal body weight and birth weight of babies between the groups. Out of 33 subjects participated in the study, 9.09 % of the subjects delivered babies with low birth weight in treatment group, while 13.6 in control group. Patients who received 5 mo and 6 mo of micronutrients showed acceptable gestational period of 34 mo. There was a significant increase in body mass index and mid abdominal circumference in treatment group (p=0.04) in comparison to the control group. Study concluded that the addition of multiple micronutrients during gestation improves pregnancy outcomes in terms of gestational week, birth weight of babies and also body mass index, mid arm circumference and mid abdominal circumference.

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Citations : 66710

Indian Journal of Pharmaceutical Sciences received 66710 citations as per google scholar report