Abstract
Efficacy of Qingshuanglu Exposure Combined with Oral Administration of Diosmin for Burn Scar Improvement and its Effect on Serum Levels of Pro-Inflammatory Factors
Wound Repair Department, The Second Affiliated Hospital of Fujian University of Traditional Chinese Medicine, 1Jianbin Traditional Chinese Medicine Surgery Clinic, Fuzhou, Fujian 3500 03, China
Correspondence Address:
Jianbin Chen, Wound Repair Department, The Second Affiliated Hospital of Fujian University of Traditional Chinese Medicine, Fuzhou, Fujian 3500 03, China, E-mail: 18650088878@163.com
To analyze the efficacy of Qingshuanglu in improving burn scars. First, 120 burn individuals were recruited and all the participants were given oral administration of diosmin and then randomized to Meibao Shi Run Shao Shang Gao and Qingshuanglu. Efficacy, visual analogue scale, vancouver scar scale score, pigmentation rate, wound drying time, healing time, safety, and serum inflammatory factor levels were comparatively analyzed. Patients receiving Qingshuanglu treatment showed shorter wound drying and healing time, lower visual analogue score, vancouver scar score, reduced pigmentation rate and total incidence of adverse reactions than those treated with Meibao. Moreover, markedly decreased levels of various serum inflammatory factors were observed in patients receiving Qingshuanglu, lower than the pre-treatment levels and those receiving Meibao. The study demonstrates that Qingshuanglu exposure could effectively repair burn injury, attenuate the inflammatory response, and reduce the scar formation for burn patients.
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