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Abstract

Evaluation of Antioxidant, Antimicrobial, Cytotoxic Potential and Elemental Analysis of Filago desertorum Whole Plant

Author(s): Abida Bano, Nadia Mushtaq*, M. Ahmad and S. Mehmood
Department of Botany, 1Department of Biotechnology, Faculty of Biological Sciences, University of science and technology, Bannu 28100, Pakistan

Correspondence Address:
Nadia Mushtaq, Department of Biotechnology, Faculty of Biological Sciences, University of science and technology, Bannu 28100, Pakistan, E-mail: [email protected]


The present study aimed to evaluate the ethanolic extract of Filago desertorum for its probable antioxidant, antimicrobial, cytotoxicity potential and to assess its elemental analysis. The ethanolic extract showed maximum 2,2-diphenyl-1-picrylhydrazyl (68.48 %), 2,2'-azino-bis-(3-ethylbenzothiazoline-6-sulfonic acid (71.32 %) and hydrogen peroxide (69.44 %) scavenging activity as compared to ascorbic acid (reference) at the concentration of 250 μg/ml. The maximum total antioxidant activity (71.53 %) and reducing power (0.197) were observed at a concentration of 250 μg/ml. The extract showed maximum percent inhibition against fungal strain Aspergillus fumigates (90 %) and bacterial strain Staphylococcus aureus (10 mm). The maximum percent mortality (70 %) was determined at 250 μg/ml concentration with half maximal inhibitory concentration of 127.00 μg/ml. Elemental analysis showed that the sodium (92.936 mg/ml) was found to be present in large amount while zinc (0.060 mg/g) was found present in low concentration but cobalt was not detected. Based on the current results, it can be concluded that Filago desertorum has maximum inhibitory, antimicrobial, cytotoxic potential and therefore can lead to antioxidant, anticancer and antibiotics agents.

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