Abstract

This study aims to explore and investigate the effectiveness of utilizing three-dimensional ultrasound speckle tracking technology to evaluate the changes in cardiac function of patients with acute exacerbation of chronic obstructive pulmonary disease that underwent treatment with N-acetylcysteine. We selected 100 patients with chronic obstructive pulmonary disease as the research subjects between December 2020 and December 2022. Then divided them into two groups according to whether it is during an acute exacerbation. Control group consisted of 50 patients without acute exacerbation, while observation group included 50 patients diagnosed with acute exacerbation. The levels of lung function-related indicators, serum-related indicators and heart function-related indicators were evaluated and compared among the different groups of patients. The results showed that observation group had better lung function-related indicators than control group (p<0.05). Observation group had arterial blood oxygen partial pressure, serum N-terminal pro-brain natriuretic peptide and serum brain natriuretic peptide levels than control group (p<0.05). Additionally, observation group had higher heart function-related indicators than control group (p<0.05). The results suggest that three-dimensional ultrasound speckle tracking technology has good clinical diagnostic value in evaluating N-acetylcysteine treatment of acute exacerbations in patients with chronic obstructive pulmonary disease. This technology can effectively reflect changes in heart function and provide guidance for the treatment plan of chronic obstructive pulmonary disease.