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Abstract

Exploration into the Clinical Value of Breast-Conserving Therapy Combined with Sentinel Lymph Node Biopsy in the Treatment of Early Breast Cancer

Author(s): Fang Fang and L. Gu*
National Clinical Research Center for Cancer, Key Laboratory of Cancer Prevention and Therapy of Tianjin, Tianjin Clinical Research Center for Cancer, 1National Clinical Research Center for Cancer, Key Laboratory of Cancer Prevention and Therapy of Tianjin, Tianjin Clinical Research Center for Cancer, Key Laboratory of Breast Cancer Prevention and Therapy (Ministry of Education), The Second Department of Breast oncology, Tianjin Medical University Cancer Institute and Hospital, Tianjin 300060, China

Correspondence Address:
L. Gu, National Clinical Research Center for Cancer, Key Laboratory of Cancer Prevention and Therapy of Tianjin, Tianjin Clinical Research Center for Cancer, Key Laboratory of Breast Cancer Prevention and Therapy (Ministry of Education), The Second Department of Breast oncology, Tianjin Medical University Cancer Institute and Hospital, Tianjin 300060, China, E-mail: [email protected]


To observe and analyze the application effect of breast-conserving therapy combined with sentinel lymph node biopsy in the treatment of early breast cancer. We selected 120 patients with early breast cancer who were treated in our hospital as subjects. Immediately thereafter, the patients were divided into study group and reference group, each with 60 cases. Different treatment plans were performed. The reference group was treated with conventional surgical mastectomy and axillary lymph node dissection. The study group was treated with breast-conserving therapy combined with sentinel lymph node biopsy. The treatment results of the two groups were observed and compared. By observing intraoperative operative time and intraoperative blood loss of the two groups, the results showed the two were significantly less in the study group than the reference group, p<0.05. In comparison of the patients postoperative quality of life and breast cosmetic results, the study group was obviously superior to the reference group, p<0.05. In addition, comparison of postoperative local recurrence rate and distant metastasis rate revealed no significant difference and there was no statistical significance, p>0.05. Treatment of early breast cancer patients with breast-conserving therapy combined with sentinel lymph node biopsy can achieve relatively good results and can significantly improve patient’s quality of life.

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