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Extractive Spectrophotometric Determination Of Iron As An Impurity In Pharmaceutical Raw Materials

Author(s): R. K Patil, D. G Dhuley

The objective of the present study is to develop an instrumental method, which is more accurate than the physical method that is followed in Indian Pharmacopoeia. A simple and sensitive spectrophotometric method has been developed for the estimation of iron as an impurity in pharmaceutical raw materials. In this method wine red color complex formed between iron and 1-3-diphenyl-4-carboethoxy pyrazole-5-one (DPCP) was measured at 525 nm. Beer's law was found to obey in the concentration range 0.5-10 μg/ml. Sandell's sensitivity and standard deviations were found to be 0.0483 μg/cm2 and±0.035 respectively.


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Citations : 53647

Indian Journal of Pharmaceutical Sciences received 53647 citations as per google scholar report