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Abstract
Formulation and evaluation of fast release lorazepam.
Author(s): GR Behra, SP Vyas, SK Jain
Dept. of Pharm. Sciences, Dr. H.S. Gour Vishwavidyalaya, Sagar (MP),
Correspondence Address:
G R Behra Dept. of Pharm. Sciences, Dr. H.S. Gour Vishwavidyalaya, Sagar (MP)
Dept. of Pharm. Sciences, Dr. H.S. Gour Vishwavidyalaya, Sagar (MP),
Correspondence Address:
G R Behra Dept. of Pharm. Sciences, Dr. H.S. Gour Vishwavidyalaya, Sagar (MP)
Solid dispersions of lorazepam were prepared using urea, PEG-6000, PEG-4000 and mannitol as carriers by temprature fusion method. These were studied for differential thermal analysis and X-ray diffraction and in vitro dissolution. In vivo absorption studies were made with promissing products, using dogs.
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