Formulation And Evaluation Of Isopropyl Antipyrine Oral Suspensions
Attempts were made in the present investigation to evolve a physico-chemically stable, elegant and palalable isopropyl antipyrine oral suspension using suspending agents like sodium carboxy methyl cellulose [Sod. CMC], veegum alone and combination of sodium CMC and microcrystalline cellulose [MCC] in varying proportions. The suspensions were subjected to evaluation and accelerated stability studies have been carried out on a few select formulations. The best formulation was found to have a shelf life of about 2.5 years and bioequivalence studies revealed comparible pharmacokinetic parameters as that of the marketed tablet.