All submissions of the EM system will be redirected to Online Manuscript Submission System. Authors are requested to submit articles directly to Online Manuscript Submission System of respective journal.

Abstract

Hemophagocytic Lymphohistiocytosis after Severe Fever with Thrombocytopenia Syndrome Virus Infection

Author(s): Q. C. WANG AND YUYU LU1*
School of Clinical Medicine, Nanjing Medical University, Nanjing, Jiangsu 210029, China, 1Department of ICU, The Affiliated Jiangning Hospital of Nanjing Medical University, Nanjing, Jiangsu 210029, China

Correspondence Address:
Department of ICU, The Affiliated Jiangning Hospital of Nanjing Medical University, Nanjing, Jiangsu 210029, China, E-mail: [email protected]

This investigation reports of a case of hemophagocytic lymphohistiocytosis caused by severe fever with thrombocytopenia syndrome bunya virus, a novel virus first described in 2011. This patient presented with high fever and laboratory study revealed the presence of thrombocytopenia. Further laboratory examinations confirmed the coexistence of severe fever with thrombocytopenia syndrome and hemophagocytic lymphohistiocytosis. Review of relevant publications led to a proposal that severe fever with thrombocytopenia syndrome as a trigger of hemophagocytic lymphohistiocytosis. More attention should be paid to severe fever with thrombocytopenia syndrome associated hemophagocytic lymphohistiocytosis and further studies be conducted

PDF