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Abstract

Hesperidin Inhibits Nitrite-Induced Methemoglobin Formation

Author(s): M Sudheer Kumar, K.K Srinivasan, M.K Unnikrishnan

Hesperidin protects hemoglobin from nitrite-induced oxidation to methemoglobin. The protection was not observed when hesperidin was added after the autocatalytic stage of the oxidation of hemoglobin. The ability of hesperidin to scavenge superoxide may be responsible since superoxide is implicated in promoting the autocatalytic stage of oxidation of hemoglobin by nitrite.

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