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Abstract

High Performance Thin Layer Chromatographic Method For Estimation Of Lovastatin From Tablets

Author(s): A. D Pillai, M. N Ravishankara, R. D Handral

A new simple, specific and precise high performance thin layer chromatographic method has been developed for estimation of lovastatin in its tablet formulations. In this method, standard solutions and sample solution of lovastatln were applied on precoated silica gel G60 F254, TLC plate and developed using toluene: methanol (75:25 v/v) as mobile phase. The plate was scanned and quantified at 239 nm for lovastatin. The method was validated for precision, accuracy and reproducibility.

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