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Abstract

Impact of Laparoscopic Ovarian Endometriosis Cystectomy on Ovarian Reserve Function

Author(s): LIMEI LIANG*, C. WANG, JUNJUN DAI AND LU LIN
Obstetrics and Gynecology Department, The First Affiliated Hospital of Bengbu Medical College, Bengbu 233003, China

Correspondence Address:
LIMEI LIANG, Obstetrics and Gynecology Department, The First Affiliated Hospital of Bengbu Medical College, Bengbu 233003, China; E-mail: [email protected]


This study was to investigate and analyze the impact of laparoscopic ovarian endometriosis cystectomy on ovarian reserve function. A total of 20 patients undergone with laparoscopic unilateral ovarian teratoma (mature cystic teratoma) cystectomy and 80 cases with ovarian endometriosis cyst given laparoscopic ovarian cystectomy were regarded as the control group and the research group, respectively. Patients in the research group were divided into four group, group A (n=20, unilateral ovarian endometriosis cyst, cyst diameter <5 cm), group B (n=20, unilateral ovarian endometriosis cyst, cyst diameter ≥5 cm), group C (n=20, bilateral ovarian endometriosis cyst, bilateral cyst diameter <5 cm) and group D (n=20, bilateral ovarian endometriosis cyst, at least one lateral cyst diameter ≥5 cm). Levels of serum follicle stimulating hormone, luteinizing hormone and estradiol for patients among groups were observed and compared. Meanwhile, follow up profiles including basic serum follicle stimulating hormone, menstruation recovery and natural pregnancy for patients at stage III at 6 mo postoperatively, at stage IV after the first return of menstruation and at 1 y postoperatively were performed, respectively. Follicle stimulating hormone levels in group C and group D after operation were significantly higher than those before operation, showing p<0.05; while luteinizing hormone and estradiol levels in group C and group D after operation were significantly lower than those before operation, showing p<0.05. No significant difference was displayed on each hormone level of patients in group A, group B and the control group between pre operation and post operation, showing p>0.05. No statistical significance was indicated on hormone levels among groups when ages and types of bilateral ovarian endometriosis cyst were observed in layering, showing p>0.05. Comparing the control group, infertile patients before operation in group A, group B and group presented a higher postoperative pregnancy rate, showing p<0.05; but postoperative pregnancy rate in group D was lower than that in the control group, showing p<0.05. Laparoscopic ovarian endometriosis cystectomy suggested certain influences on ovarian reserve function. Most patients could recover at 1 y postoperatively and the postoperative pregnancy rate for fertile patients could be significantly enhanced by adding gonadotropin releasing hormone agonist, a medicine after the operation.

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