All submissions of the EM system will be redirected to Online Manuscript Submission System. Authors are requested to submit articles directly to Online Manuscript Submission System of respective journal.
Abstract
In Vitro Cytotoxic Studies Of Mannich Bases Of ?-Diketones
Author(s): R Rajesh, A. A Siddiqui, G. V. S Ramasarma, V Alagarsamy
In vitro cytotoxic activity of some 2-(N-aryl/heteroaryl aminomethyl)-1,3-diphenyl/1-phenyl-3-(3- nitrophenyl)/1-phenyl-3-(pyridin-3-yl)propan-1,3-diones were determined by adopting three methods (Trypan blue dye exclusion, Lowry, MTT, 3-(4,5-dimethyl thiazol-2-y1)-2,5-diphenyl tetrazo- lium bromide assay) using HEp-2 cell cultures. Among the compounds tested the compound Vlll was found to be superior in its cytotoxicity in all the three methods.
PDF
