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In vitro evaluation of anthelmintic activity of Nauclea orientalis leaves

Author(s): S. T. V. Raghavamma, N Rama Rao
Chalapathi Institute of Pharmaceutical Sciences, Chalapathi Nagar, Lam, Guntur-522 034, India

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E-mail: [email protected]

Antianthelmintic activity of successive extracts (chloroform, acetone, ethanol and aqueous) of Nauclea orientalis leaves were evaluated separately on adult Indian earthworm (Pheretima posthuma) and compared with that of albendazole. It was found that the extracts exhibited, respectively dose-dependent action and inhibition of spontaneous motility (paralysis) and death of earthworms. The results indicated that the chloroform, ethyl acetate and ethanol extracts were more potent.

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