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Abstract

Insights of Pharmacological Activities, Patents and Clinical Applications of Polyphenolic Compounds Enriched Nuts of Juglans regia: A Review

Author(s): Roopal Mittal1, Prerna Goel2, Vivek Verma1 and Amit Mittal3,4*
Department of Pharmacy, I. K. G Punjab Technical University, Jalandhar, Punjab 144601, 1R. K. S. D College of Pharmacy, Kaithal, Haryana 136027, 2School of Medical and Allied Sciences, G. D. Goenka University, Gurugram, Haryana 122103, 3Department of Pharmaceutical Chemistry, School of Pharmaceutical Sciences, Lovely Professional University, Phagwara, Punjab 144411, 4Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Desh Bhagat University, Mandi Gobindgarh, Punjab 147301, India

Correspondence Address:
Amit Mittal, Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Desh Bhagat University, Mandi Gobindgarh, Punjab 147301, India, E-mail: amitmittal77@yahoo.com

Juglans regia L. is a wonder nut widely used as functional food owing to its multi-nutritional qualities. It is generally found in Southeast Europe extending towards the Himalayas and Southwest China. This historical plant is extensively used ethno-medicinally in the treatment of digestive, respiratory, cardiovascular and skin diseases. Its seeds are highly proteinaceous and polyphenolic containing triacylglycerol-rich oil especially mono and polyunsaturated fatty acids. The diverse lipid profile of the walnut has attracted the researchers of the decade towards scientific validation of its traditional aspects and isolation of important chemical compounds for improving human health. The present review comprehends the ameliorative effect of Juglans regia on various chronic diseases including cancer, gut dysbiosis, cardiovascular and neurodegeneration concerning its specific chemical profile.

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