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Investigating the Effects of Remimazolam and Propofol on Awakening Quality and Cognitive Function in after Hysteroscopy: A Comparative Study

Author(s): Guangmin Feng, Yong Yin and Jie Zhang*
Department of Anesthesiology, Huashan Hospital, Fudan University of Shanghai, 1Department of Anesthesiology, Civil Aviation Hospital of Shanghai, Shanghai 200336, China

Correspondence Address:
Y. Yin, Department of Anesthesiology, Civil Aviation Hospital of Shanghai, Shanghai 200336, China, E-mail:

To explore the differences in awakening quality and cognitive function in patients who received remimazolam vs. propofol anesthesia during hysteroscopy. One hundred patients undergoing laparoscopic surgery at our hospital from March 2022 to August 2022 were randomly allocated to either an observation group or a control group. The control group received anesthesia induction with propofol and remifentanil, and maintained during surgery, while the observation group received anesthesia induction with remifentanil and maintained during surgery. Hemodynamic indicators, including heart rate, mean arterial pressure, and respiratory rate were compared between the groups at various time points. The steward recovery score was used to assess patients' recovery quality, and the mini-mental state examination was used to evaluate postoperative cognitive function recovery. In the remazolam group, the changes of mean arterial pressure and respiratory frequency were smaller, the Steward awakening score was higher during awakening, and the cognitive function score was higher after extubation. The performance of remimazolam is better than that of propofol, which indicates that remimazolam may be a better drug choice.

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