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Abstract

Kinetics Of Release Of Pentazocine Hydrochloride From Mictropellets Of Ethylcellulose And Eudragit RL-100

Author(s): M Mandal, B. K Gupta

Micropellets of Pentazocine hydrochloride were fabricated by the emulsion – solvent – evaporation method using different combinations of ethylcellulose and Eudragit RL 100. The polymer combinations, drug load, and pH of the dissolution medium were found to extert important effects on the drug release profiles. Release kinetics also showed a heterogeneous pattern.

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