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Meta-Analysis of Safety and Efficacy of Different Radical Gastrectomy in the Treatment of Gastric Cancer

Author(s): Tipeng Zhang, Junbao Liu, Changbin Liu, Qijie Wang, Yanli Bian and Cheng Wang*
Department of Clinical Medicine, Zhengzhou Shuqing Medical College, Zhengzhou, Henan 450064, 1Department of Traditional Chinese Medicine, Henan Provincial People’s Hospital, Zhengzhou, Henan 450008, 2Department of Traditional Chinese Medicine, Hospital of Traditional Chinese Medicine, Cangzhou, Hebei 061000, 3Department of Gastroenterology, Zhengzhou Yangcheng Hospital, Zhengzhou, Henan 452470, 4Zhengzhou Shuqing Medical College, Zhengzhou, Henan 450064, China

Correspondence Address:
Cheng Wang, Zhengzhou Shuqing Medical College, Zhengzhou, Henan 450064, China, E-mail:

To investigate the safety and efficacy of different radical gastric cancer treatments in the management of gastric cancer. The literature published in the last 5 y was searched for recent outcomes of different radical gastric cancer procedures used in the treatment of gastric cancer. 14 papers were finally included according to the established screening criteria. The trial design, study population characteristics and findings of the included studies were abstracted using randomized independent trials and statistically analyzed using RevMan 5.0 software. The results of the meta-analysis showed that laparoscopic early distal gastric cancer surgery compared with conventional open surgery: The operative time was 49.85 min longer (p<0.05), but intraoperative bleeding was 145.50 ml less (p<0.05), the number of postoperative analgesic requests was 1.22 less (p=0.01) and the number of days to the first postoperative vent was 0.57 d shorter (p<0.05), the number of days to the first postoperative meal was shortened by 0.88 d (p<0.05); the number of postoperative hospital days was shortened by 4.76 d (p<0.05) and the incidence of postoperative complications was low, both differences were statistically significant (p<0.05). The recent efficacy of laparoscopy-assisted distal gastrectomy in treating gastric cancer was significantly better than that of conventional open distal gastrectomy.

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