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Abstract

Microwave-assisted synthesis of an important intermediate of benazepril

Author(s): B Mistry1, Dipti Medhane2, Krishnapriya Mohanraj1, Sanjeevani A Ghone1
1 Department of Pharmaceutical Chemistry, Bombay College of Pharmacy, Kalina, Santacruz (E) Mumbai - 400 098, India 2 School of Pharmacy & Technology Management, SVKM's NMIMS, Vile Parle (W), Mumbai - 400 056, India

Correspondence Address:
Sanjeevani A Ghone Department of Pharmaceutical Chemistry, Bombay College of Pharmacy, Kalina, Santacruz (E) Mumbai - 400 098 India E-mail: [email protected]


Rapid and efficient methods for the synthesis of an important intermediate of benazepril ethyl 3-phthalimido-2,3,4,5-tetrahydro-1H-[1]benzazepin-2-one-1-acetate under the influence of microwave irradiation are described. A comparative study of conventional and microwave assisted method is briefly discussed.

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