All submissions of the EM system will be redirected to Online Manuscript Submission System. Authors are requested to submit articles directly to Online Manuscript Submission System of respective journal.


Neocuproine And Bathocuproine As New Reagents For Sensitive Spectrophotometric Determination Of Certain Dibenzazepine Drugs

Author(s): N. G Keshvachar, Ayesha Syeda, M. A Pasha, A. A Syed

Two new reagents, neocuproine and bathocuproine are proposed for simple, sensitive and selective spectrophotometric methods for the determination of dibenzazepine class of drugs. In the proposed method copper (lI) reacts with imipramine hydrochloride, desipramine hydrochloride, clomipramine hydrochloride, trimipramine maleate and opipramol and subsequently with neocuproine or bathocuproine in an acetic acid medium to yield yellow or orange-red colour, with maximum absorption at 460 or 480 nm, respectively. A reaction mechanism is proposed with drug - metal and reagent ratio of 1:2.


Google scholar citation report
Citations : 53647

Indian Journal of Pharmaceutical Sciences received 53647 citations as per google scholar report