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Abstract

Nursing Mode for Advanced Gastric Carcinoma with Combined Application of Domestic Tegafur Gimeracil Oteracil Potassium and Oxaliplatin

Author(s): X. Ba, J. Han*, G. Zhao and Yu Mu
Department of Radiotherapy, 1Department of Colorectal and Anal Surgery, The Second Hospital of Jilin University, Changchun 130041, China

Correspondence Address:
J. Han, Department of Radiotherapy, The Second Hospital of Jilin University, Changchun 130041, China, E-mail: [email protected]


To observe and analyze the nursing method for advanced gastric carcinoma with combined application of domestic tegafur gimeracil oteracil potassium and oxaliplatin. 160 patients who had been diagnosed with advanced gastric carcinoma in our hospital were selected as research objects and all of them were applied with therapy of domestic tegafur gimeracil oteracil potassium and oxaliplatin. During treatment, targeted nursing mode was implemented to overcome relevant toxic reaction. The nursing effect was observed and analyzed. After implementation of nursing, all patients were applied with chemotherapy regimen successfully and the total treatment effective rate reached 78.13 %. During treatment with combined application of domestic tegafur gimeracil oteracil potassium and oxaliplatin, the main toxic reactions were peripheral neurotoxicity, leukopenia, thrombocytopenia, diarrhea, nausea, vomiting, phlebitis, etc. The comparison of mental status score before and after nursing showed that the mental status was significantly better after nursing, p<0.05. During treatment of advanced gastric carcinoma with combined application of domestic tegafur gimeracil oteracil potassium and oxaliplatin, implementing targeted nursing can significantly reduce toxic reactions.

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