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Abstract

Postoperative Curative Effect of Docetaxel and Nedaplatin Combined Chemotherapy in Advanced Gastric Carcinoma

Author(s): H Tian, J Shang, Z Ji, Rongrong Me, D Su, Y Wang and D Ke*
First Affiliated Hospital of Jiamusi University, Jiamusi, 154002, China

Correspondence Address:
First Affiliated Hospital of Jiamusi University, Jiamusi, 154002, China, E-mail: [email protected]

The present study was aimed to analyze the postoperative curative effect of combined chemotherapy with docetaxel and nedaplatin in advanced gastric carcinoma. In this study, 160 patients with advanced gastric carcinoma were enrolled as study subjects. They underwent radical gastrectomy and were randomly divided into the study group and the control group, each containing 80 patients. The control group was treated with oxaliplatin, leucovorin and 5-fluorouracil combined chemotherapy. The study group was treated with docetaxel, nedaplatin combined chemotherapy. There was no significant difference in short-term treatment efficiency between the two groups. In terms of 1-year survival rate and 3-year survival rate, the study group was better than the control group, p<0.05. There was no significant different in rate of adverse reactions between the two groups. The study group showed better quality of life relative to the control group. For treatment of advanced gastric carcinoma, docetaxel-nedaplatin combination could achieve relatively satisfactory long-term efficacy

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