All submissions of the EM system will be redirected to Online Manuscript Submission System. Authors are requested to submit articles directly to Online Manuscript Submission System of respective journal.

Abstract

Preformulation Compatability Study Between Metoprolol Tartrate And Tablet Excipients Using Differential Scanning Calorimetry (DSC)

Author(s): E. K Iyer, H. P Tipnis

Differential scanning calorimetry (DSC) was employed as a tool to investigate the physico-chemical compatability between metoprolol tartrate and a number of commonly used excipients. Metoprolol was found to be compatable with microcrystalline cellulose (Avicel PH 101®), Eudragit® and colloidal silicon dioxide (Aerosil®). Although metoprolol showed interactions with stearic acid, magnesium stearate, lactose, sodium carboxymethyl starch/sodium starch glycollate (Primojel®), Indian CRP 234and starch, one cannot conclusively state that interaction incompatabilities will occur on storage at room temperature.

PDF

 
 
List of Supporting Conferences