Abstract
Relationship between Obstructive Sleep Apnea Hypopnea Syndrome Complicated with Various Types of Hypertension and Plasma Homocysteine Level
Department of Critical Care Medicine, West China Hospital, Sichuan University, 1Department of Anesthesiology, Chengdu Jinjiang Maternity and Child Health Hospital, Chengdu, Sichuan 610000, China
Correspondence Address:
Bo Liu, Department of Anesthesiology, Chengdu Jinjiang Maternity and Child Health Hospital, Chengdu, Sichuan 610000, China, E-mail: liubojjfy@163.com
To investigate the relationship between obstructive sleep apnea hypopnea syndrome complicated with various traditional Chinese medicine syndromes of hypertension and plasma homocysteine level, patients were divided into liver-fire excess syndrome, yin deficiency and yang excess syndrome, phlegm-blood stasis syndrome, yin deficiency and yang deficiency syndrome based on the traditional Chinese medicine syndrome type standard of hypertension complicated obstructive sleep apnea hypopnea syndrome. General data, body mass index values, apnea and hypopnea index, oxyhemoglobin saturation, Epworth sleepiness scale scores and homocysteine of patients were extracted and analyzed. The results revealed that the number of males was greater than that of females with a proportion of 1.5:1. The number of patients with body mass index ≥24.00 kg/m2 was obviously greater than that of patients with body mass index <24.00 kg/m2. The proportion of patients with body mass index >28.00 kg/m2 reached 59.18 %. In terms of the comparison of traditional Chinese medicine syndrome types, the proportion of patients suffering from phlegm-blood stasis syndrome was the highest, reaching 27.89 % and the proportion of patients suffering from yin deficiency and yang deficiency syndrome is the lowest, amounting to 22.45 %. In homocysteine examination, the homocysteine of syndrome was increased in order of yin deficiency and yang excess, phlegm-blood stasis, yin deficiency and yang deficiency and liver-fire excess. The results revealed that the syndrome type of phlegm-blood stasis was significant among patients with obstructive sleep apnea hypopnea syndrome in the distribution of traditional Chinese medicine syndrome types. This syndrome type showed significant statistical meaning in age, neck circumference, apnea and hypopnea index, average oxyhemoglobin saturation, triglyceride and overall difference in blood glucose fasting state. The severity of obstructive sleep apnea hypopnea syndrome was positively correlated with homocysteine and apnea, and hypopnea index was also positively correlated with homocysteine and was negatively correlated with lowest oxygen saturation. Lowest oxygen saturation was negatively correlated with homocysteine.
