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Release Rate Of Diclofenac Sodium From Different Polymers

Author(s): V Prabhakar Reddy, A Suneeta

Diclofenac sodium (DS) tablets were formulated employing different polymers such as cellulose acetate (5% and 10%) eudragit RS 100 (10 and 20%) in different concentrations. These formulations were evaluated for thickness, hardness, friability, weight variation, drug content uniformity and in vitro dissolution rate testing. The in vitro dissolution rate studies of DS from different polymers were compared with marketed formulations. The drug release pattern of these DS tablets was slow compared to commercial brands.


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