Role of Circular RNA in Melanoma Development: A Mini Review
Department of Cosmetic Plastic Surgery, Chengdu Second People’s Hospital, Chengdu, Sichuan, China , 1Department of Cosmetic Plastic and Burn Surgery, West China Hospital Sichuan University, Chengdu, Sichuan, China , 2Division of Geriatrics, Sichuan Academy of Medical Sciences and Sichuan Provincial People’s Hospital, Chengdu, China
Division of Geriatrics, Sichuan Academy of Medical Sciences and Sichuan Provincial People’s Hospital, Chengdu, China, E-mail: firstname.lastname@example.org
The Malignant melanoma, a tumor derived from melanocytes, shows severe drug resistance and prompt metastasis, causing a serious threat to human health. Emerging evidence indicates that circular RNAs are widely expressed in mammals and play crucial role in tumorigenesis by regulating micro RNA, downstream gene expression and protein production. The role of circular RNA in pathogenesis of melanoma has been recently reported and highlighted. This review makes and attempt to provide a better insight in to the role of circular RNA in melanoma.