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Simultaneous reverse phase HPLC estimation of some antiretroviral drugs from tablets

Author(s): Nandini Pai, AD Desai
D. G. Ruparel College, Mahim, Mumbai-400 016, India

Correspondence Address:
Nandini Pai D. G. Ruparel College, Mahim, Mumbai-400 016 India E-mail: [email protected]

A simple, precise, fast and selective HPLC method has been developed for the simultaneous estimation of lamivudine, zidovudine and nevirapine from tablets by external standard method. The analytes were resolved by using mobile phase of 50:50 mixture of methanol:buffer (0.1 M ammonium acetate in 0.5% glacial acetic acid) on an Inertsil ODS 3V (250 × 4.6 mm, 5 µ) column as a stationary phase and UV 270 nm as detection wavelength.

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