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Simultaneous Spectrophotometric Estimation Of Pheylpropanolamine HCl, Bromhexine HCI And Chlorpheniramine Maleate

Author(s): S. K Panda, A. K Sharma

Present communication deals with simultaneous analysis of three component formulation containing phenyl propanolamine HCl [PPA], bromhexine HCl [BH] and chlorpheniramine maleate [CPM], by multicomponent analysis method. PPA, BH and CPM showed linearity with absorbances in the range of 0-1000 mg/ml, 0-80 mg/ml and 0-60 mg/ml at the corresponding sampling wavelengths 257 nm, 305 nm and 272 nm respectively. The results obtained in analysis of syrup samples have been statistically validated and were found satisfactory. The method is simple, accurate and rapid.


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