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Spectro Photometric Determination Of Promethazine Using Sodium Nitroprusside

Author(s): K Basavaiah, G Krishnamurthy

A simple, accurate and rapid method for the quantitative determination of promethazine in either pure form or in pharmaceutical formulations is proposed. The method is based on the formation of red product with sodium nitroprusside in sulphuric acid medium having maximum absorption at 515nm.