All submissions of the EM system will be redirected to Online Manuscript Submission System. Authors are requested to submit articles directly to Online Manuscript Submission System of respective journal.

Abstract

Spectrophotometric Estimation Of Itraconazole In Pharmaceutical Formulations

Author(s): T. K Murthy, M. N Reddy, Y Srinivasa Rao, D. G Sankar

Two simple spectrophotometric methods (A and B) have been developed for the determination of itraconazole in pure and in its pharmaceutical formulations. Method A is based on the formation of blood red colored complex with ferric chloride and 1,10-phenanthroline having absorption maximum at 520 nm, where as in method B, itraconazole forms a green colored complex with ferric chloride and MBTH reagent exhibiting maximum absorption at 630 nm .The chromogens obey Beer's law in the concentration ranges of 1.2 to 7.5 μg/ml and 2.5 t o 20 μg/ml for methods A and B, respectively. The results obtained are reproducible and are statistically validated.

PDF

 
 
Google scholar citation report
Citations : 69022

Indian Journal of Pharmaceutical Sciences received 69022 citations as per google scholar report