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Spectrophotometric Estimation Of Piperazine In Dosage Forms Using Dichlone And Acetaldehyde As Reagent

Author(s): C. J Shishoo, B. N Suhagia, I. S Rathod, S. S Thakore

A simple spectrophotometric method for the determination of Piperazine Citrate in bulk drug and dosage forms is described. The method is based on the reaction between piperazine and 2,3-dichloro-1, 4-naphthoquinone in presence of acetaldehyde to give a violet colored product having lmax at 580nm. The results are comparable with those obtained by official method.


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