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Spectrophotometric Estimation Of Valdecoxib In Pure Form And Tablets

Author(s): V. B Sutariya, Rajashree Mashru, M. G Sankalia, Priti Parikh

Simple UV and third derivative spectrophotometric methods have been developed for the determination of valdecoxib in bulk drug and its tablets. In simple UV spectrum of valdecoxib in 0.1 N sodium hydroxide, it exhibits absorption maxima (λmax) at 243 nm where as in third derivative spectrum it shows maxima at 221.2 nm and minima at 213.6 nm. Both the methods were found to be simple, economical, accurate, reproducible and can be adopted in routine analysis of valdecoxib in bulk drug and its tablets.


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